GraphDx: A Cost-Aware Knowledge-Enhanced Multi-Agent Framework for Sequential Diagnosis

Abstract

arXiv:2607.15280v1 Announce Type: new Abstract: Sequential diagnosis requires balancing diagnostic accuracy against resource costs through iterative information gathering. Existing Large Language Model (LLM) approaches exhibit a critical knowledge-reasoning gap: despite encoding extensive medical knowledge, they struggle to reason systematically under cost constraints, often resorting to excessive testing. We propose GraphDx, a knowledge-enhanced framework with two core innovations. First, we de